diff --git a/config b/config
index b9df376..9c7b8a9 100644
--- a/config
+++ b/config
@@ -34,6 +34,8 @@ ciphers =
 dns_lookup = True
 # Root URL of Radicale (starting and ending with a slash)
 base_prefix = /
+# Possibility to allow URLs cleaned by a HTTP server, without the base_prefix
+can_skip_base_prefix = False
 # Message displayed in the client when a password is needed
 realm = Radicale - Password Required
 
diff --git a/radicale/__init__.py b/radicale/__init__.py
index 8451e43..376973a 100644
--- a/radicale/__init__.py
+++ b/radicale/__init__.py
@@ -252,6 +252,9 @@ class Application(object):
             environ["PATH_INFO"] = self.sanitize_uri(
                 "/%s" % environ["PATH_INFO"][len(base_prefix):])
             log.LOGGER.debug("Sanitized path: %s", environ["PATH_INFO"])
+        elif config.get("server", "can_skip_base_prefix"):
+            log.LOGGER.debug(
+                "Skipped already sanitized path: %s", environ["PATH_INFO"])
         else:
             # Request path not starting with base_prefix, not allowed
             log.LOGGER.debug(
diff --git a/radicale/config.py b/radicale/config.py
index f6ac6f0..3ba983e 100644
--- a/radicale/config.py
+++ b/radicale/config.py
@@ -49,6 +49,7 @@ INITIAL_CONFIG = {
         "ciphers": "",
         "dns_lookup": "True",
         "base_prefix": "/",
+        "can_skip_base_prefix": "False",
         "realm": "Radicale - Password Required"},
     "encoding": {
         "request": "utf-8",